Neuroblastoma is the most common extracranial malignant neoplasm in infants and children.

It accounts for eight to 10% of all childhood cancers and 15% of cancer related death.

The median agent diagnosis is usually 22 months with 30 % of cases being discovered in the first year of life.

The tumors arise from the neural crest cells of the sympathetic nervous system.

The abdomen particularly the adrenal is the most common site for this tumor to appear.

The most commonly occur in the abdomen (65%) followed by the chest, neck and pelvis.

Ultrasound appearance

On ultrasound you may encounter a round or ovoid mass with mixed echogenicity often time does the punctate echogenic foci representing classifications.

Right adrenal Neuroblastoma with metastasis to the liver.
Retroperitoneal Neuroblastoma
Retroperitoneal Neuroblastoma causing biliary obstruction.
Neuroblastoma encasing the Aorta, SMA and Celiac artery


Townsend, C. M., Beauchamp, R. D., Evers, B. M., Mattox, K. L., & Sabiston, D. C. (2022). Sabiston textbook of surgery: The biological basis of modern surgical practice. St. Louis, MO: Elsevier.

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