Neuroblastoma is the most common extracranial malignant neoplasm in infants and children.

It accounts for eight to 10% of all childhood cancers and 15% of cancer related death.

The median agent diagnosis is usually 22 months with 30 % of cases being discovered in the first year of life.

The tumors arise from the neural crest cells of the sympathetic nervous system.

The most commonly occur in the abdomen (65%) followed by the chest, neck and pelvis.

Ultrasound appearance

On ultrasound you may encounter a round or ovoid mass with mixed echogenicity often time does the punctate echogenic foci representing classifications.

Right adrenal Neuroblastoma with metastasis to the liver.

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Retroperitoneal Neuroblastoma

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Retroperitoneal Neuroblastoma causing biliary obstruction.

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Neuroblastoma encasing the Aorta, SMA and Celiac artery

Sources:

Townsend, C. M., Beauchamp, R. D., Evers, B. M., Mattox, K. L., & Sabiston, D. C. (2022). Sabiston textbook of surgery: The biological basis of modern surgical practice. St. Louis, MO: Elsevier.